photo H. Cottet 0622

Hervé Cottet


Professor in Analytical Chemistry

Institut des Biomolécules Max Mousseron

Université de Montpellier, UMR CNRS 5247, ENSCM

Place Eugène Bataillon,  Case courrier 1706

34095 Montpellier Cedex 5, France


Phone : (+33) 4 67 14 34 27
Fax : (+33) 4 67 63 10 46

Email :


  Research Interests

Electrokinetic separation techniques (free solution, gel, micellar, isoelectric focusing, isotachophoretic, 2D and frontal modes)
Taylor Dispersion Analysis 

Characterization of polyelectrolytes, biopolymers and colloïds
Study of biomolecule interactions (stoichiometry, affinity constants)
Electrophoretic mobility modelling
Capillary coatings (SMIL)
Characterization and study of bacteria
Dendrigraft Poly-L-lysine


Curriculum Vitae




Industrial and academic programs



  Recent papers (2018-2020): complete list here

P127. Study of interactions between antigens and polymeric adjuvants in vaccines by frontal analysis continuous capillary electrophoresis. C. Malburet, L. Leclercq, J.-F. Cotte, J. Thiebaud, H. Cottet. Biomacromolecules, 2020, submitted.

P126. Quantification of adsorption and optimization of separation of proteins in Capillary Electrophoresis. L. Leclercq, C. Renard, M. Martin, H. Cottet. Anal. Chem., 2020, submitted.

P125. Mass transfer efficiency in rare earths extraction using a hollow fiber pertraction device. M. Toure, J. Chamieh, G. Arrachart, S. Pellet-Rostaing, H. Cottet, J. Duhamet, Separation and Purification Technology, 2020, submitted.

P124. Co-solvents in self-emulsifying drug delivery systems (SEDDS) – do they really solve our solubility problems? A. Jörgensen, J. Friedl, R. Wibel, J. Chamieh, H. Cottet, A. Bernkop-Schnürch, Molecular Pharmaceutics, 2020, under revision.

P123. Capillary Zone Electrophoresis-Top-Down Tandem Mass Spectrometry for in-depth Characterization of Hemoglobin Proteoforms in Clinical and Veterinary Samples. A. Stolz, Y. Hedeland, L. Salzer, J. Römer, R. Heiene, L. Leclercq, H. Cottet, J. Bergquist, C. Neusüß, Anal. Chem., 2020, under revisions.

P122. Characterization of diblock copolymers by capillary electrophoresis: From electrophoretic mobility distribution to distribution of composition. A. Phimphachanh, J. Chamieh, L. Leclercq, J. Pinaud, S. Harrisson, M. Destarac, P. Lacroix-Desmazes, C. Gérardin, M. In, H. Cottet, Macromolecules, 2020, 53, 334-345.

P121. Optimizing Water-based Extraction of Bioactive Principles of Hawthorn: from Experimental Laboratory Research to Homemade Preparations. P. Cao Ngoc, L. Leclercq, J.-C. Rossi, I. Desvignes, J. Hertzog, A.-S. Tixier, F. Chemat, P. Schmitt-Kopplin, H. Cottet, Molecules, 2019, 24, 4420.

P120. Superhydrophobic capillary coatings: elaboration, characterization and application to electrophoretic separations. C. Renard, L. Leclercq, A. Stocco, H. Cottet, J. Chromatogr. A, 2019, 1603, 361–370.

P119. Size-based characterization of polysaccharides by Taylor Dispersion Analysis with photochemical oxidation or back scattering interferometry detections. L. Leclercq, P. Saetear, A. Rolland-Sabaté, J.-P. Biron, J. Chamieh, L. Cipelletti, D. J. Bornhop, H. Cottet, Macromolecules, 2019, 24, 2328.

P118. Characterization of hydrosoluble fraction and oligomers in poly(vinylidene chloride) latexes by capillary electrophoresis using electrophoretic mobility modeling. A. Ibrahim, H. Cottet, J. Chromatogr. A., 2019, 1598, 223-231.

P117. Supramolecular self-assembly of DNA with a cationic polythiophene – From polyplexes to fibers. M. Leclercq,  J. Rubio-Magnieto, D. Mohammed, S. Gabriele, L. Leclercq, H. Cottet, S. Richeter, S. Clément, M. Surin, ChemNanoMat, 2019, 5, 703-709.

P116. Peptide release from SEDDS containing hydrophobic ion pair therapeutic peptides measured by Taylor dispersion analysis. J. Chamieh, A. Domènech Tarrat, C. Doudou, V. Jannin, F. Demarne, H. Cottet, Int. J. Pharm., 2019, 559, 228-234.

P115. Modulation of the electroosmotic mobility using polyelectrolyte multilayer coatings for protein analysis by capillary electrophoresis. L. Leclercq, M. Morvan, J. Koch, C. Neusuess, H. Cottet, Analytica Chimica Acta, 2019, 1057, 152-161.

P114. Mobility shift affinity capillary electrophoresis at high ligand concentrations: application to aluminum chlorohydrate – protein interactions. N. Ouadah, C. Moire, F. Brothier, J.-F. Kuntz, M. Malý, P. Dubský, H. Cottet, ACS Omega, 2018, 3, 12, 17547-17554.

P113. Separation and characterization of highly charged polyelectrolytes by free solution capillary electrophoresis. I. Desvignes, J. Chamieh, H. Cottet, Polymers, 2018, 10, 1331.

P112. Capillary electrophoresis for aluminum ion speciation: optimized separation conditions for complex polycation mixtures. N. Ouadah, C. Moire, F. Brothier, J.-F. Kuntz, O. Deschaume, C. Bartic, H. Cottet, J. Chromatogr. A, 2018, 1552, 79-86.

P111. Size-characterization of natural and synthetic polyisoprenes by Taylor dispersion analysis. J. P. Biron, F. Bonfils, L. Cipelletti, H. Cottet, Polymer Testing. 2018, 66, 244-250.

P110. Effect of dendrigraft generation on the interaction between anionic polyelectrolytes and dendrigraft poly-L-lysine. F. Lounis, J. Chamieh, L. Leclercq, P. Gonzalez, J. C. Rossi, H. Cottet, Polymers 2018, 10, 45.

P109. Size characterization of lipid-based self-emulsifying pharmaceutical excipients during lipolysis using Taylor dispersion analysis with fluorescence detection. J. Chamieh, H. Merdassi, J.-C. Rossi, V. Jannin, F. Demarne, H. Cottet, Int. J. Pharm., 2018, 537, 94-101.



    Junior Member of the Institut Universitaire de France (IUF), 2011-2016.

    Awardee 2016 of the French Scholar Series (Peter Wall Institute for Advanced Studies and Frenh Consulate Vancouver)

    Award "Chercheur d'Avenir", Région Languedoc-Roussillon, 2010-2013.

    Award from the French Chemical Society (Analytical Chemistry Division), 2006.

    Lauréat ACI jeunes chercheurs (French National Research Agency), 2004-2008.


Last update: June 10, 2020.

Taylor dispersion analysis, capillary electrophoresis, polyelectrolyte complexes, characterization of polymers, nanoparticles, dendrigraft polymers, dendrimers, analysis of bacteria; analysis of polymers, drug delivery systems. Expertise en électrophorèse capillaire. Consultance en électrophorèse capillaire. Expertise and consultancy in capillary electrophoresis and Taylor dispersion analysis.